Amidst the ongoing COVID-19 pandemic, with vaccines and therapies yet to be made widely available and definitely applicable for all ages including those with co-morbidities, an unique biological response modifier glucan (BRMG) called Nichi Glucan derived from a black yeast called Aureobasidium pullulans (AFO-202), manufactured in Japan has been suggested to have potential as a food supplement based vaccine adjuvant for COVID-19, as it can act as an immune-modulating Beta Glucan on all the arms of immunity., viz., innate, adaptive, mucosal and trained immunity (TRIM) to exert its effector actions in a balanced manner.
Nichi Glucan has the following advantages to be consumed as a continuous nutritional supplement in your daily life,
✔One of its kind water soluble beta-glucan; can be mixed with food, drink or consumed as such.
✔ Manufactured in a GMP facility in Japan, approved as food additive in 1996.
✔It has been in consumption in Japan by people of all ages as a food supplement.
✔ It has potential to balance blood glucose and lipid levels when consumed regularly . A clinical pilot study has reported that the HbA1C could be well balanced; published in peer reviewed journal. (https://doi.org/10.1155/2012/895370)
✔Very high lipid levels was reported to be brought under control in another clinical study (https://doi.org/10.3109/19390211.2013.859211)
✔Its potential as wide-spectrum immune-balancing food-supplement-based enteric (β-WIFE) vaccine adjuvant approach to COVID-19 has been recently published wherein it could help in COVID-19 by virtue of its cytokine balancing effects, metabolic effects and ability to function in coagulation pathways in a beneficial manner as people with co-morbidities such as diabetes, dyslipidaemia and those with high risk of coagulopathy leading to stroke are vulnerable to develop severe COVID-19 (https://doi.org/10.1080/21645515.2021.1880210).
✔Nichi Glucan has been able to help in anti-cancer immunity in studies done in Japan in cancer patients and elderly healthy volunteers. Clinical research is ongoing to use it as a supportive therapy for management of gut dysbiosis because of its prebiotic potentials.
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Nichi Glucan is available commercially as a food supplement. For a better health and immunity, arm yourself by taking Nichi Glucan daily as a food supplement.
For enquiries: info@gncorporation.com
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