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Singapore develops innovative magnetic gel to heal diabetic wounds faster

20 October 2023 | News

First-of-its-kind cell therapy promotes wound healing, improves overall wound health and lowers risks of recurrence

Diabetic patients, whose natural wound-healing capabilities are compromised, often develop chronic wounds that are slow to heal. Such non-healing wounds could cause serious infections resulting in painful outcomes such as limb amputation.

To address this global healthcare challenge, a team of researchers from the National University of Singapore (NUS) have engineered an innovative magnetic wound-healing gel that promises to accelerate the healing of diabetic wounds, reduce the rates of recurrence, and in turn, lower the incidents of limb amputations.

Each treatment involves the application of a bandage pre-loaded with a hydrogel containing skin cells for healing and magnetic particles. To maximise therapeutic results, a wireless external magnetic device is used to activate skin cells and accelerate the wound healing process. The ideal duration of magnetic stimulation is about one to two hours.

Lab tests showed the treatment coupled with magnetic stimulation healed diabetic wounds about three times faster than current conventional approaches. Furthermore, while the research has focused on healing diabetic foot ulcers, the technology has potential for treating a wide range of complex wounds such as burns.

The researchers are conducting more tests to further refine the magnetic wound-healing gel to improve its effectiveness. They are also collaborating with a clinical partner to test the effectiveness of the gel using diabetic human tissues.

Every year, there are around 9.1 to 26.1 million cases of diabetic foot ulcer worldwide, and around 15 to 25 per cent of patients with diabetes will develop a diabetic foot ulcer during their lifetime. Singapore has one of the highest rates of lower limb amputation due to diabetes globally, averaging around four per day. 

 

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