China's CanSino Biologics Inc. announced on 13 August 2020 that it has successfully listed on the Sci-Tech Innovation Board (STAR Market) of the Shanghai Stock Exchange, making it the first "A+ H" dual listing vaccine company. CanSinoBIO will issue 24.8 million shares at the issue price of RMB209.71 per Share.

The funds will provide full support to the construction of the second phase manufacturing facility, vaccine research and development, vaccine traceability, the construction of a cold chain logistics system and an information system, as well as the supplementary working capital.

Dr. Xuefeng Yu, chairman and chief executive officer of CanSinoBIO, said: "The launch of STAR Market and the reform of HKEX listing have provided policy support for biopharmaceutical companies that require continuous long-term, large-scale investments for research and development of vaccine candidates. It allows companies to have branding benefits and make global strategic plans."

CanSinoBIO is dedicated to the research, development, manufacturing and commercialization of high-quality vaccines for human use. CanSinoBIO has developed four key platform technologies, including adenovirus-based viral vector vaccine, conjugation, protein structure design and recombination as well as vaccine formulation technologies. In addition, it has in-licensed a number of core intellectual properties.

CanSinoBIO is currently developing 16 vaccine candidates for 13 infectious disease areas, including meningitis, pneumonia, tuberculosis, COVID-19, Ebola virus disease, pertussis, diphtheria, tetanus, shingles etc.

Among them, the recombinant Ebola virus vaccine (Ad5-EBOV), jointly developed by CanSinoBIO and the Beijing Institute of Biotechnology, Academy of Military Medical Sciences (BIB), has obtained approval in China. The two meningococcal conjugate vaccines under research are close to commercialization, among which the quadrivalent meningococcal conjugate vaccine is the first of its kind in China that has been granted priority review designation by the China National Medical Products Administration (NMPA).

In March 2020, the Recombinant Novel Coronavirus Vaccine (the “Ad5-nCoV”), a vaccine candidate co-developed by CanSinoBIO and BIB, became the world's initial vaccine candidate to enter the clinical research stage. The two phases of the clinical trial have now been completed and the results have already been published on the Lancet journal. In June, the vaccine received China’s military specially-needed drug approval with a valid period of one year.

In addition, the Pneumococcal vaccine portfolio, DTcP vaccine portfolio, TB Booster and several other innovative vaccines are currently under clinical trial stage or pre-clinical research stage.