Topic: High-throughput single-cell multiomics in characterizing basophils and decoding tumor micro-environment

Synopsis:

Despite being the rarest granulocytes, basophils play crucial roles in immunity. However, their extreme fragility and sensitivity to handling have historically hampered study, leading to their underrepresentation in droplet-based single-cell sequencing studies. Thankfully, this is changing. Microwell-based single-cell analysis, with its high sensitivity, is unlocking a new era of basophil research at an unprecedented pace. This breakthrough is revealing previously unknown secrets about these enigmatic cells, advancing our understanding of their functions and contributions to health and disease.

Furthermore, high-resolution single-cell multiomics analysis is shedding light on the complex cellular landscape and immune regulatory mechanisms in non-small cell lung cancer (NSCLC). This powerful approach promises to improve our understanding of disease progression and response to treatment, potentially leading to the development of more personalized and effective therapies.

Join us for this exciting webinar where:

• Professor Kensuke Miyake, a leading expert in basophil biology, will share his latest research, revealing how single-cell RNA sequencing is unlocking the secrets of these enigmatic cells.
• Dr. Hyun-Woo Jeong, a pioneer in single-cell multiomics, will showcase how this cutting-edge technology is helping to decode the complex tumor microenvironment in non-small cell lung cancer (NSCLC) and discuss how these advancements are leading to a deeper understanding of lung cancer, paving the way for more effective treatments and personalized medicine approaches.

The presenters will discuss:

• Unexpected findings: How advanced technology revealed previously unknown basophil precursor cells and recent progress in single-cell sequencing enabled basophils biology.
• Unlocking mysteries: Unraveling the complex tumor microenvironment using state-of-the-art single-cell analysis.

Key Learning Objectives:
Highly sensitive single cell RNA sequencing enables the comprehensive characterization of hard to sequence basophils and subsequent identification of basophils precursor cells. Furthermore large scaled single-cell multiomics study is advancing the understanding of the formation and function of TLS in shaping clinical outcomes of NSCLC.

Speakers: