Thursday, 25 April 2024


Axol Bioscience introduces Human iPSC-derived Atrial Cardiomyocytes

18 July 2018 | News

A consistent and reproducible model for drug development, toxicity testing and disease modelling applications

Axol Bioscience Ltd., a biotechnology company, provides human cell culture systems and custom services for disease modeling and drug discovery markets. The company produces human cells and critical reagents, which include media and growth supplements.

 

The company has launched their Human iPSC-derived Atrial Cardiomyocytes for the discovery and development of novel treatments and advancing our understanding of cardiovascular disease.

 

Generated from the same donor as Axol’s highly validated Human iPSC-derived Ventricular Cardiomyocytes, this physiologically relevant human iPSC-derived cell line is quick and easy to use, ready in just 7-days from thaw, for electrophysiology, cardiac contractility study, screening and the investigation of cardiomyopathies.

 

Validated through an industry recognised third party and validated against the Comprehensive in vitro Pro-arrhythmia Assay (CiPA) guidelines, Axol’s Human iPSC-derived Atrial Cardiomyocytes express typical targets, ion channels and currents (Kv1.5, Ikir3.x, Ikur, IKACh, MLC2a & ANP) essential for the screening of cross target effects, the development of atrial specific target drugs, and the investigation of atrial fibrillation and inherited cardiac conditions.

 

According to Yichen Shi, Chief Executive Officer, Axol Bioscience, they are the first and only iPSC-derived atrial cardiomyocyte product currently available to the research market.

 

The overall potential and application of the Human iPSC-derived Atrial Cardiomyocytes can be enriched when cultured with Axol’s serum-free Cardiomyocyte Maintenance Medium, reducing variability and enhancing consistency in their culture.

Sign up for the editor pick and get articles like this delivered right to your inbox.

Editors Pick
+Country Code-Phone Number(xxx-xxxxxxx)


Comments

× Your session has been expired. Please click here to Sign-in or Sign-up
   New User? Create Account